首页> 外文会议>Society for Biomaterials annual meeting and exposition >Modulation of Cellular Response Using Mechanically Dynamic PDMS Substrates
【24h】

Modulation of Cellular Response Using Mechanically Dynamic PDMS Substrates

机译:使用机械动态PDMS底物调节细胞反应。

获取原文

摘要

Conclusions: We present an orthogonal crosslinking strategy to fabricate mechanically dynamic PDMS substrates, where the viscoelasticity and stiffness of the PDMS substrates can be temporal and spatial controlled using light. These photoresponsive PDMS substrates are cytocompatible and can be applied to regulate the cell morphology, showing a strong correlation between substrate stiffness and cell spreading and elongation. These results demonstrate the photoresponsive PDMS substrates provides a promising platform to study cell-matrix interactions in a dynamic manner.
机译:结论:我们提出了正交交联策略来制造机械动态的PDMS基板,其中PDMS基板的粘弹性和刚度可以使用光来进行时间和空间控制。这些光敏PDMS底物具有细胞相容性,可用于调节细胞形态,显示底物刚度与细胞铺展和伸长之间有很强的相关性。这些结果表明,光响应性PDMS底物为以动态方式研究细胞-基质相互作用提供了一个有前途的平台。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号