Effect of hormone levels, gender, body mass index, age and life-style parameters on human craniofacial bone #regeneration with tricalcium phosphate grafts

摘要

Introduction: Augmentation of the maxillary sinus has become a well-established pre-implantology procedure for alveolar ridge augmentation of the posterior maxilla. Over the last decade, the use of tricalcium phosphate (TCP) particles as alloplastic bone graft material for sinus floor augmentation procedures (SFA) has received increasing attention in implant dentistry. However, little is known regarding the effect of patient-specific parameters such as hormone levels, gender, body mass index (BMI), age and life-style parameters on bioactive ceramic stimulated bone regeneration. Expanding this knowledge base, however, is of great importance, with respect to tailoring and optimizing treatment regimes for individual patients in view of pursuing an individualized orofacial medicine. The objective of this study was to elucidate the associations between these patient-specific factors and bone formation after SFA, when utilizing a bioactive TCP grafting material.