首页> 外文会议>Iranian Conference on Electrical Engineering >Exploring the disorders of brain effective connectivity network in ASD: A case study using EEG, transfer entropy, and graph theory
【24h】

Exploring the disorders of brain effective connectivity network in ASD: A case study using EEG, transfer entropy, and graph theory

机译:探索ASD中大脑有效连接网络的疾病:使用EEG,转移熵和图论的案例研究

获取原文

摘要

Many people worldwide suffer from Autism Spectrum Disorder (ASD) which is a neurodevelopmental disorder. It severely degrades the subjects' communication skills. The earlier diagnosing of ASD, The higher probability to prevent the severity of ASD symptoms. In the recent decade, brain connectivity studies on ASD subjects have converged to the theory of under-connectivity as a biomarker of ASD. Most of these studies have used fMRI data rather than EEG/MEG data and investigated functional connectivity rather than effective connectivity. There are few EEG/MEG studies which investigated the effective connectivity disorders in ASD subjects. Also, to the best of our knowledge there is no published study to investigate the disorders of brain effective connectivity networks in ASD subjects using EEG data, nonlinear effective connectivity measures and graph theory. In this paper, we aim to start filling this gap. We used EEG data, transfer entropy with self-prediction optimality, and four graph theoretic parameters to compare the effective connectivity networks of ASD youths with those of healthy controls (HCs) during a passive face processing task. Our results showed a significant difference in average degree (p<;0.05) between ASD and HC groups which is consistent with the under-connectivity theory of ASD. On the other hand we detected no significant changes in total clustering coefficient, average path length, and longest path length.
机译:全球许多人患有自闭症谱系障碍(ASD),这是一种神经发育障碍。它严重降低了受试者的沟通能力。诊断ASD越早,预防ASD症状严重程度的可能性就越高。在最近的十年中,关于ASD受试者的大脑连通性研究已经融合到连通性不足理论作为ASD的生物标记。这些研究中的大多数都使用了功能磁共振成像数据而不是EEG / MEG数据,并且研究了功能连通性而非有效连通性。很少有EEG / MEG研究调查ASD受试者中的有效连通性障碍。另外,据我们所知,尚无发表的研究使用EEG数据,非线性有效连接度量和图论研究ASD受试者的大脑有效连接网络障碍。在本文中,我们旨在填补这一空白。我们使用EEG数据,具有自我预测最优性的传递熵和四个图形理论参数来比较被动面部处理任务期间ASD青年与健康对照(HCs)的有效连通性网络。我们的结果表明,ASD和HC组之间的平均程度存在显着差异(p <; 0.05),这与ASD的连通性不足理论相一致。另一方面,我们检测到总聚类系数,平均路径长度和最长路径长度没有明显变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号