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Robust and high sensitivity biosensor using injection locked spin torque nano-oscillators

机译:使用注入锁定自旋扭矩纳米振荡器的鲁棒性和高灵敏度生物传感器

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Magnetic nano-particles have been used in biological assays for bio-sensing applications [1]. A wide variety of biological species - such as cells, proteins, antibodies, pathogens, toxins, and DNA - can be labeled by attaching them to magnetic nano-beads (fig. 1). Magnetic nano-particles are non-toxic, stable, non-reactive (in most biological assays) and scalable, and hence, can be highly useful for developing cost-effective, high-sensitivity and reliable point-of-care bio-sensing techniques. Field induced magneto-resistive signal produced by nano-scale magnetic tunnel junctions (MTJ) can offer a sensitive and scalable mechanism for detecting the magnetic nano-tags [1]. An MTJ can be operated as Spin Torque Nano Oscillator (STNO) which constitutes of a thin insulating oxide sandwiched between two ferromagnetic layers (Fig. 1). The ferromagnetic layers have two stable spin-polarization states, depending upon magnetic anisotropy. The magnetization of one of the layers is fixed, while that of the other (free-layer) can be influenced by a charge current passing through the device or by an applied magnetic field. The high-polarity fixed magnetic-layer spin-polarizes the electrons constituting the charge-current, which in turn exert spin transfer torque (STT) on the free layer. STT results in precession of the effective spin moment of the free layer away from the original magnetization axis, while an inherent inertial damping torque tries to restore it along the original state. [2] A static magnetic field can be used to obtain sustained spin-precession of the free layer at an angle Φ, at which the STT and the damping torque balance out each other. (Fig. 2a) The dynamics of the free layer is governed by the Landau-Lifshitz-Gilbert Slonczewski Equation. [2].
机译:磁性纳米颗粒已用于生物检测中的生物检测[1]。通过将各种生物物种附着到磁性纳米珠上,可以对它们进行标记(如细胞,蛋白质,抗体,病原体,毒素和DNA)(图1)。磁性纳米粒子无毒,稳定,无反应(在大多数生物测定中)且可扩展,因此对于开发具有成本效益,高灵敏度和可靠的即时医疗生物传感技术非常有用。纳米级磁性隧道结(MTJ)产生的场感应磁阻信号可以提供灵敏且可扩展的机制来检测磁性纳米标签[1]。 MTJ可以用作自旋扭矩纳米振荡器(STNO),它由夹在两个铁磁层之间的薄绝缘氧化物组成(图1)。根据磁各向异性,铁磁层具有两个稳定的自旋极化状态。一层的磁化强度是固定的,而另一层(自由层)的磁化强度会受到流过器件的充电电流或施加的磁场的影响。高极性固定磁性层使构成电荷电流的电子自旋极化,进而在自由层上施加自旋传递转矩(STT)。 STT导致自由层的有效自旋力矩脱离原始磁化轴,而固有的惯性阻尼扭矩试图使其沿原始状态恢复。 [2]静磁场可用于获得自由层在角度Φ上的持续自旋进动,在该角度上STT和阻尼扭矩彼此平衡。 (图2a)自由层的动力学受Landau-Lifshitz-Gilbert Slonczewski方程控制。 [2]。

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