Utilize Compositing Strategy to Simultaneously Enhance the Adhesive Properties and Bioactivity of Synthetic PEG-based Bioadhesive

摘要

Chemically crosslinked gelatin microgels were incorporated into dopamine-modified PEG-based adhesive. Increasing mcirogel content decreased cured time and increased the mechanical and adhesive properties of the composite adhesive. Gelatin microgels also enhanced fl-broblast attachment and onto the surface of the adhesive. The incorporation of gelatin microgel presents a simple method to simultaneously enhance the adhesive property and bioactivity of an injectable and bioinert PEG-based adhesive.