Implementing the concept of dielectrophoresis in glomerular filtration of human kidneys

摘要

This paper describes a possible application of dielectrophoretic force (FDEP) in glomerular filtration part of mimic human kidney blood filtration process. In an electrokinetics occurrence, a miniaturized array type of two poles microelectrodes has been simulated, fabricated, and tested using engineered particles. The particles can be attracted laterally towards or repelled vertically from the regions of strong intensity electric field, depending upon whether the particles are more or less polarisable than the suspending medium. The FDEP response is further improved by application of tapered DEP electrode profile. The finding of this work is possible to contribute in medical sciences research such as integration of DEP into a lab on a chip (LOC) for application in filters implemented in artificial kidney.