A biosensor platform based on Raman spectroscopy of porous silicon

摘要

Porous silicon suitable for optical detection as a biosensor platform is fabricated. The morphology, structure and Raman properties of porous silicon have been studied and protein P38 of Echinococcus granulosus was determined by the porous silicon Raman intensity changes following protein P38 of Echinococcus granulosus molecule adsportion. The results of the tests indicated that, when antigen is added into the porous silicon, the Fourier transform Raman intensity decrease of porous silicon is also increasing.