Based on the wind tunnel data, the NEXT treatment using a buffered genipin reagent was able to reduce the deflections and vibrations of the soft palate. The audio recordings results from the in vivo study supported the wind tunnel results with a decrease in amplitude at high frequencies of the soft palate during snoring. However, the audio results did show a reduction in amplitude in the low frequency range, which could be due to low frequency background noise, such as exercise wind, that was encountered during the audio recordings. Additionally, the in vivo study completely cured DDSP for at least one of the three horses, supporting the efficacy of the NEXT product to prevent soft palate displacements. Potential future projects include DDSP equine studies to further analyze the efficacy of NEXT. The ultimate goal would be to apply this study to human soft palates for snoring and sleep apnea applications.
展开▼
