Conjugation of Bicyclol-Polymer Conjugates for Protecting Liver from Injury

摘要

The bicyclol containing water soluble copolymers were prepared by radical polymerization and polymerization modification approach. The bicyclol conjugated copolymers were not toxic to Huh7-SJR12 replicon cells. The solubility of bicyclol in water was significantly improved by conjugating bicyclol on to the HPMA polymer. The future study will focus on bicyclol conjugated polymer protection from liver injury.