EDTA loaded BSA nanoparticles for targeted therapy to reverse vascular calcification in chronic kidney disease animal model

摘要

We were able to produce BSA nanoparticles loaded with chelating agent EDTA. These nanoparticles showed a sustained release of the EDTA in 4-5 days as desirable. We aim to use these nanoparticles to target vascular calcification induced in uremic rats by adenine injection and study the reversal of calcification. These studies are underway and results will be presented.