Poly(ε-caprolactone)/gelatin composite electrospun scaffolds with porous crater-like structures for tissue engineering

摘要

We developed a highly porous PCL/gelatin composite electrospun scaffold with crater-like structures as a tissue engineering scaffold. Crater-like structures provide an interconnected porous network within the electrospun scaffold, and gelatin incorporation into PCL allows the scaffold to possess bioactivity as well as structural stability. These characteristics of the composite scaffold enable it to structurally and biochemically replicate the 3-D ECM microenvironment. which provides a novel solution to the current challenges of electrospun scaffolds.