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Class Aware Exemplar Discovery from Microarray Gene Expression Data

机译:从微阵列基因表达数据中获得类感知示例发现

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Given a dataset, exemplars are subset of data points that can represent a set of data points without significance loss of information. Affinity propagation is an exemplar discovery technique that, unlike k-centres clustering, gives uniform preference to all data points. The data points iteratively exchange real-valued messages, until clusters with their representative exemplar become apparent. In this paper, we propose a Class Aware Exemplar Discovery (CAED) algorithm, which assigns preference value to data points based on their ability to differentiate samples of one class from others. To aid this, CAED performs class wise ranking of data points, assigning preference value to each data point based on its class wise rank. While exchanging messages, data points with better representative ability are more favored for being chosen as exemplar over other data points. The proposed method is evaluated over 18 gene expression datasets to check its efficacy for selection of relevant exemplars from large datasets. Experimental evaluation exhibits improvement in classification accuracy over affinity propagation and other state-of-art feature selection techniques. Class Aware Exemplar Discovery converges in lesser iterations as compared to affinity propagation thereby dropping the execution time significantly.
机译:对于给定的数据集,示例是数据点的子集,可以表示一组数据点,而不会丢失重要的信息。亲和传播是一种示例性发现技术,与k中心聚类不同,它对所有数据点都具有统一的优先级。数据点以迭代方式交换实值消息,直到具有其代表性示例的簇变得明显为止。在本文中,我们提出了一种类感知示例发现(CAED)算法,该算法根据数据点区分一类样本与另一类样本的能力为数据点分配偏好值。为此,CAED会对数据点进行分类排名,并根据每个数据点的分类排名为每个数据点分配优先级值。在交换消息时,具有更好表示能力的数据点比其他数据点更适合作为示例。该方法在18个基因表达数据集中进行了评估,以检查其从大型数据集中选择相关样本的有效性。实验评估显示,与亲和力传播和其他最新特征选择技术相比,分类精度有所提高。与亲缘关系传播相比,类感知示例发现在更少的迭代中收敛,从而显着减少了执行时间。

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