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Novel Stent Design for Percutaneous Aortic Valve Replacement

机译:经皮主动脉瓣膜置换的新型支架设计

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Background: Vascular support structures are important devices for treating valve stenosis. Large population of patients are treated for valvular disease and the principal mode of treatment is the use of Percutaneous Valvuloplasty. Stent devices are proving to be an improved technology in minimal invasive cardiac surgery. This stent technology now accounts for 20% of treatments in Europe. This new technology provides highly Effective results at minimal cost and short duration of hospitalization. Methods: This paper discusses the design of vascular support structures (stents) for Percutaneous Aortic Valve Replacement. The improved model design was carried out to meet the functional and surgical requirements. Results: Different geometrical models were generated and their physical, mechanical and behavioral properties were studied. Structural analysis and simulation of these models enhanced the designer to optimize the geometry suitable for performance during and after implantation. Conclusion: The blunt hooks discussed in the designs enable the aorta to take the shape of the stent thus preventing its migration in either directions without injuring its endothelium. The stent port size prevents obstruction of the coronary blood flow. Future studies will determine if this novel stent design will fulfill the unmet clinical needs in Percutaneous Aortic Valve Replacement.
机译:背景:血管支撑结构是治疗阀狭窄的重要装置。对瓣膜疾病进行治疗的大群患者,主要的治疗方式是使用经皮胰腺成形术。支架设备在急性侵袭性心脏手术中被证明是一种改进的技术。这种支架技术现在占欧洲的20%。这种新技术以最低的成本和较短的住院时间提供了高效的结果。方法:本文讨论了血管支持结构(支架)的经皮主动脉瓣膜置换。进行了改进的模型设计以满足功能性和手术要求。结果:产生了不同的几何模型,研究了它们的物理,机械和行为性能。这些模型的结构分析和仿真增强了设计者,以优化适合于植入期间和之后的性能的几何形状。结论:设计中讨论的钝钩使得主动脉使支架的形状取得,从而防止其在任一方面的迁移而不会损伤其内皮。支架口径尺寸可防止冠状动脉血流阻塞。未来的研究将确定这种新型支架设计是否会在经皮主动脉瓣膜置换中满足未满足的临床需求。

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