Elastomeric Electrospun Poly(glycerol sebacate) via a Water-Soluble Carrier Polymer

摘要

We developed an electrospinning approach to obtain thermally crosslinked elastomeric PGS fibrous structures. The process does not require coaxial set-ups or chemical crosslinkers. Additionally, PVA is removed by aqueous washes, producing true PGS fibers that preserve the mechanical and cytocompatible properties of PGS sheet and foam. This fabrication method permits more complex structures to be fabricated by fibrous PGS. Future work will focus on optimizing the protocols and producing inductive scaffolds for in situ tissue engineering.