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A Configurable Portable System for Ambulatory Monitoring of Gastric Bioelectrical Activity and Delivering Electrical Stimulation

机译:一种可配置的便携式系统,用于胃生物电活动的动态监测和输送电刺激

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The purpose of this paper is to develop and validate a configurable system that can wirelessly acquire gastric electrical activity called slow waves, and deliver high energy electrical pulses to modulate its activity. The system is composed of a front-end unit, and an external stationary back-end unit that is connected to a computer. The front-end unit contains a recording module with four channels, and a stimulating module with two channels. Commercial off-the-shelf components were used to develop front- and back-end units. A graphical user interface (GUI) was designed in LabVIEW to process and display the recorded data in real-time, and store the data for off-line analysis. Besides, the gain of the analog conditioning circuit as well as the stimulation pulse configuration is programmable directly through the GUI. The system was successfully validated on bench top. The bench-top studies showed an appropriate frequency response for analog conditioning and digitization resolution to acquire gastric slow waves. Moreover, the system was able to deliver electrical pulses at amplitudes up to ±24 mA and ±12 mA to a load of up to 0.5 kΩ and 1 kΩ, respectively. This study reports the first high-energy stimulator that can be controlled wirelessly and integrated into a gastric bioelectrical activity monitoring system. The system can be used for treating functional gastrointestinal disorders.
机译:本文的目的是开发和验证可配置的系统,可以无线地获取称为慢波的胃电活动,并提供高能电脉冲以调节其活动。该系统由前端单元组成,以及连接到计算机的外部静止后端单元。前端单元包含具有四个通道的记录模块,以及具有两个通道的刺激模块。商业现成部件用于开发前端和后端单元。在LabVIEW中设计了一个图形用户界面(GUI),以实时处理和显示录制的数据,并存储数据进行离线分析。此外,模拟调节电路的增益以及刺激脉冲配置可直接通过GUI进行编程。该系统在台面上成功验证。台面研究表明,用于模拟调节和数字化分辨率的适当频率响应,以获取胃慢波。此外,该系统能够分别以高达±24 mA的幅度递送电脉冲,±12 mA至高达0.5kΩ和1kΩ的载荷。本研究报告了第一高能量刺激器,可以无线控制并集成到胃生物电活动监测系统中。该系统可用于治疗功能性胃肠道障碍。

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