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Ampoule and Nozzle Development for Needle-Free Injections

机译:针刺注组和喷嘴开发用于无针注射

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A rigid, compact, multi-piece ampoule has been designed and fabricated as a platform to conveniently house different nozzle inserts one at a time to offer increased jet consistency and functional flexibility. Three different nozzle geometries that respectively produce a single axial jet, radial jets, and intersecting jets are designed and fabricated. Through high-speed imaging and injection into tissue analog and ex vivo porcine tissue, these nozzles are demonstrated to have potential for a range of injection applications including intradermal, intratympanic, and traditional uses. The presented ampoule is more successful than a commercial jet injection ampoule in adhering to desired position and velocity trajectories and the energy efficiencies of jet ejections are compared.
机译:一款刚性,紧凑,多件式安瓿设计和制造为平台,以便在一次方便地铺设不同的喷嘴,以提供更高的射流一致性和功能灵活性。设计并制造了三种不同喷嘴几何形状,分别产生单个轴向射流,径向喷射器和交叉喷射器。通过高速成像和注射到组织类似物和离体猪组织中,这些喷嘴被证明具有一系列注射应用,包括皮内,尿道和传统用途。呈现的安瓿比在粘附到所需位置和速度轨迹的商业喷射安瓿中更成功,并且比较喷射喷射的速度轨迹。

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