Automated Control of Blood Glucose in the OR and Surgical ICU

摘要

A device which integrates existing intravenous continuous glucose monitors and infusion pumps into a central hub for automated intravenous intensive insulin therapy, targeting non-diabetic critically-ill patients is presented. Additionally, a fuzzy logic based controller that is capable of automatically making closed-loop decisions to achieve tight glycemic control between a euglycemic range of 90 to 120 mg/dl is presented. Initial bench top testing shows a significant improvement in glycemic control with fuzzy logic control when compared to manual infusion protocols currently used in hospitals; future animal testing will be performed to verify these results in vivo.