Purpose: Radiofrequency (RF) ablation is a common treatment modality for inoperable liver cancer. Skin burns below ground pads during RF ablations are increasingly prevalent, hindering the development of higher-power RF generators capable of creating larger ablation zones. Materials and Methods: 9 RF ablations (n=4 simultaneous, n=5 sequential) were performed with 300W for 12 min via two internally cooled cluster electrodes placed in the gluteus maximus of domestic swine. Three ground pads placed on the animal's abdomen were activated either simultaneously, or sequentially where activation timing was adjusted to equilibrate skin temperature below each pad. Temperature rise at each pad was compared. Ablation zone dimensions were determined via MRI. Results: Maximum temperature rise was significantly higher with simultaneous activation than with sequential activation (21.4 vs 8.1 °C, p<0.01). Ablation zone diameters during simultaneous and sequential activation were 6.9±0.3 and 5.6±0.3, respectively. Conclusion: Sequential activation of multiple ground pads resulted in significantly lower skin temperatures during high-power RF ablation.
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机译:目的:射频(RF)消融是肝癌不可操作的常见治疗方式。在RF消融期间,皮肤燃烧地下焊盘越来越普遍,妨碍了高功率RF发电机的开发,能够产生更大的消融区域。材料和方法:通过在国内猪的辉光峰值中的两个内部冷却的簇电极进行300W,通过300W进行300W进行12次RF消融(n = 4同时,n = 5顺序)。置于动物腹部上的三个接地垫同时被激活,或者顺序地激活,其中调节激活定时以平衡每个垫的皮肤温度。比较每个垫的温度升高。通过MRI确定消融区尺寸。结果:同时激活大于顺序激活的最高温度升高(21.4 Vs 8.1°C,P <0.01)。同时和顺序激活期间的消融区直径分别为6.9±0.3和5.6±0.3。结论:多个接地垫的顺序激活导致高功率RF消融期间的皮肤温度明显降低。
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