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Emergency hospital admissions for cardiorespiratory diseases and PM10 chemical composition in Hong Kong

机译:香港因心肺疾病和PM10化学成分而急诊入院

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Background: Research on how individual chemical components of PM affect human health has been focusing on fine particles (i.e., PM2.5). PM composition differs by size, with more crustal materials in coarser PM and more combustion-related components in finer PM, and thus their associated health risks could differ. Evidence regarding the health impacts on PM10 chemical composition is scarce.Aims: We examined the short-term association between PM10 composition and daily emergency hospital admissions in Hong Kong.Methods: Twenty-four hour concentrations of PM10 mass and eighteen components from six general air monitoring stations, daily cardiovascular (CVD) and respiratory (RESP) hospital admission data and meteorological measurements were obtained. Generalized additive models were used for the analysis.Results: Between 2001-2007, daily average concentration of PM10 mass in Hong Kong was 54.3 μg/m3. Major contributors to PM10 included organic matter (OM), sulfate, elemental carbon (EC), nitrate, and ammonium. After adjusting for weather, seasonal/time trends, day-of-week and influenza epidemic, an inter-quartile range increment in nitrate (3.4 μg/m3) was associated with 1.8% (95% CI: 1.1-2.5 at lag 0 day) and 1.6% (95% CI: 1.0-2.3 at lag 3 day) increase in CVD and RESP hospital admissions respectively. Similar associations with OM were also found. EC, trace metals (iron, nickel, vanadium) and water-soluble ions (ammonium, sodium, potassium, chlorine ion) were linked with increased hospital admissions, particularly in the cool season. Stronger effects were observed for admissions among elderly (065 years) and RESP admissions among men.Conclusions: Ambient levels of secondary particles (nitrate) and OM that is primarily from combustion were associated with the largest risks of hospital admissions across the PM10 components in Hong Kong. Potential seasonal influence and effect modifiers for PM10 composition-related health effects warrant further investigation.
机译:背景:关于PM的各个化学成分如何影响人类健康的研究一直集中在微粒(即PM2.5)上。 PM的组成因尺寸而异,粗颗粒中的地壳材料更多,而细颗粒中的燃烧相关成分更多,因此其相关的健康风险可能有所不同。缺乏有关健康对PM10化学成分影响的证据目的:我们研究了PM10成分与香港每日急诊入院之间的短期关联性方法:24小时浓度的PM10物质和六种普通空气中的18种成分监测站,获得每日心血管(CVD)和呼吸(RESP)住院数据和气象数据。结果:2001-2007年间,香港PM10的每日平均浓度为54.3μg/ m3。 PM10的主要贡献者包括有机物(OM),硫酸盐,元素碳(EC),硝酸盐和铵。在调整了天气,季节/时间趋势,一周中的某天和流感流行之后,硝酸盐(3.4μg/ m3)的四分位数间距增加与滞后0天的1.8%(95%CI:1.1-2.5)相关)和CVD和RESP住院人数分别增加了1.6%(在滞后3天时95%CI:1.0-2.3)。还发现了与OM相似的关联。欧共体,痕量金属(铁,镍,钒)和水溶性离子(铵,钠,钾,氯离子)与住院人数的增加有关,尤其是在寒冷季节。在老年人(065岁)和男性的RESP住院患者中观察到了更强的效果。结论:主要来自燃烧的二次颗粒(硝酸盐)和OM的环境水平与本港PM10组件中住院的最大风险相关孔与PM10成分相关的健康影响的潜在季节影响和影响调节剂有待进一步研究。

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