Mortality from rnale laryngeat cancer in the Southeastern Brazilian

摘要

Background: The larynx is one of the most common site of occurrence of neoplams in the head and neck. In Brazil, laryngeal cancer was responsible for 3,6% of deaths from cancer in men and 0,6% in women between 2005 and 2009. Many environmental factors and lifestyle-related are associated with its development. Tabacco and alcohol consumption are the most established risk factors for this disease. However, occupational exposure to carcinogens are also associated. Aims: To analyze the mortality trends of male laryngeal cancer in the Southeastern Brazilian geographic regions between 1980 and 2010. Methods: A descriptive study was realized using data on male laryngeal cancer deaths registered in the Mortality Data System (SIM/WHO) and population data were provided by Brazilian Institute of Geography and Statistics (IBGE). Age-standardized and specific mortality rates were calculated. Linear regression and Estimated Annual Percentage Changes (EAPC) were used to investigate changes in trends for the each State of Southeastern Brazilian. Results: Laryngeal cancer deaths were more common in men after the fifty decade of life. Considering the states of Brazilian Southeastern, the annual age-standardized mortality rate increased in Espirito Santo and Minas Gerais (EAPC=1,31% and 0,60%, respectively), between 1980 and 2010. However, decreases were found in Rio de Janeiro (EAPC=-1,09%) and Sao Paulo (EAPC=-0,70%). Conclusions: The Brazilian states of southeastern showed different trends in male mortality from laryngeal cancer. These findingsimplythe importance to improve tabacco control measures and excessive alcohol consumption, as well as monitoringof occupational exposure. Furthermore, measures for diagnosis and early treatment may impact on mortality by this disease.