Combating dental caries via restorative materials containing antibacterial and remineralizing nanoparticles

摘要

Dental caries at the margins of restorations has been the main reason for restoration failure. Restorative dental materials such as resin composite and adhesive systems are in contact with tooth and can be the ideal vehicle for delivering anticaries agents. Based on nanotechnology, nanoparticles of silver (NAg) were introduced into restorative materials to achieve antimicrobial properties. Another strategy to combat caries lesions around restorations is to drive the shift of demineralization to remineralization process via calcium (Ca) or phosphate (P) ion release. This was achieved via resins filled with nanoparticles of amorphous capcium phosphate (NACP). In the present contribution we report the development of restorative materials including primer, adhesive and composites that containing NAg and NACP. The antibacterial, remineralizing and mechanical properties of these new materials indicate that novel nano-sized agents can fight bacteria and reduce the demineralization in restored tooth cavities.