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Gene Tree Correction by Leaf Removal and Modification: Tractability and Approximability

机译:通过去除和修饰叶片的基因树校正:可牵引性和近似性

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The reconciliation of a gene tree and a species tree is a well-known method to understand the evolution of a gene family in order to identify which evolutionary events (speciations, duplications and losses) occurred during gene evolution. Since reconciliation is usually affected by errors in the gene trees, they have to be preprocessed before the reconciliation process. A method to tackle with this problem aims to correct a gene tree by removing the minimum number of leaves (Minimum Leaf Removal). In this paper we show that Minimum Leaf Removal is not ap-proximable within factor 6 log m, where m is the number of leaves of the species tree and b > 0 is a constant. Furthermore, we introduce a new variant of the problem, where the goal is the correction of a gene tree with the minimum number of leaf modifications. We show that this problem, differently from the removal version, is W[1]-hard, when parameterized by the number of leaf modifications.
机译:基因树和物种树的和解是一种了解基因家族进化过程的众所周知的方法,以便确定在基因进化过程中发生了哪些进化事件(物种,重复和损失)。由于和解通常受基因树错误的影响,因此必须在和解过程之前对其进行预处理。解决该问题的方法旨在通过去除最少的叶子(最小去除叶子)来校正基因树。在本文中,我们显示最小叶子去除率在6 log m的范围内不是近似的,其中m是物种树的叶子数,b> 0是一个常数。此外,我们引入了该问题的新变体,其目标是用最少的叶子修饰次数纠正基因树。我们显示,与删除版本不同,此问题在通过叶修改的数量进行参数化时是W [1] -hard。

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