Micron/Nano Hierarchical Topography of Titanium Surface Influences Adhesion and Multi-differentiation #Behaviours of Mesenchymal Stem Cells

摘要

Conclusions: A highly orientated cellular morphology and a larger cellular elongation appeared on Hybrid. In addition, hMSCs cultured on this Hybrid topography were strongly promoted the osteogenic and chondrogenic differentiation. This hierarchical topography fabricated by femtosecond laser irradiation possibly contributes to achieve next generation implants.