Studying the Synergistic Effect of Coatings and Nitric Oxide release on Platelet Adsorption

摘要

Zwitterionic polymers, especially pCB and pSB, have been applied to a wide range of biomedical and engineering materials. pCB , pSB and R3 random copolymer modified surfaces have shown high resistance to nonspecific protein fouling. Our current challenge now is testing these coatings against more complex biological media, ultimately blood, for longer flow durations. The preliminary data herein show a promising approach for meeting these challenges.