Cell-laden hydrogel beads, fibers and plates for 3D tissue construction

摘要

In this presentation, I will talk about the recent activity of our group to fabricate thick, highly-dense, heterogeneous 3D tissue structures using MEMS/Microfluidic technology. We prepare cell-laden micro beads, micro fibers and micro plates as building blocks for the 3D construction; the 3D cellular structures can be formed by molding, weaving, and folding of each block. These techniques will be useful for the construction of large-scale 3D tissue architectures that mimic the morphology and function of living tissues in vivo.