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Production of Functional Microtool Using Size-Classified Gel-Microbeads

机译:使用尺寸分类的凝胶微珠生产功能微池的生产

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In this study, we succeeded in producing functional microtool made of gel-microbead using size-dependent microparticle classification. Gel-microbead, which is used as the material for the microtool, is made by salting-out of hydrophilic photo-crosslinkable resin, ENT-3400. These gel-microbeads were separated according to their size by microfilters made of polydimethylsiloxane (PDMS). A first on is a row of fluidic micro-channels which block microbeads with a size over the width of the channel. Another filtering method has been experimented, using Magnetically driven MicroTool (MMT) to separate the beads using the centrifugal force created by this MMT actuated with a DC motor. Separated gel-microbeads were recovered after filtering step and then used to fabricate functional microtools, for example tether-shaped gel-tool, by contact to other gel-microbeads under UV illumination. Produced gel-tool is manipulated by optical tweezers in a microchip. We succeeded in getting size-dependent separation of the gel-microbeads and production of the tether-shaped gel-tool.
机译:在这项研究中,我们成功地生产了使用尺寸依赖性微粒分类的凝胶微粒制成的功能性微池。用作微池的材料的凝胶微珠通过盐酸盐,ent-3400制成。通过由聚二甲基硅氧烷(PDMS)制成的微型滤光器,根据其尺寸分离这些凝胶微珠。首先是流体微通道的一排,该流体微通道阻挡了尺寸在通道的宽度上的微珠。使用磁驱动微池(MMT)进行了另一种滤波方法,以使用通过用DC电动机致动的该MMT产生的离心力分离珠子。过滤步骤后回收分离的凝胶微珠,然后通过在UV照明下与其他凝胶微珠接触来制造官能微池,例如系醚形凝胶工具。由微芯片中的光学镊子操纵产生的凝胶工具。我们成功地获得了凝胶微珠的尺寸依赖性分离,并产生系绳形凝胶工具。

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