Improvement of Hemocompatibility by coatings of zwitterionic and PEG based copolymers under physiological flow conditions

摘要

Poly(SBMA-co-AA) and poly(PEGMA-co-AA-g-Az) copolymers modified surfaces possess excellent resistance to platelet adhesion under both static and shear conditions. The reuslts suggest that the synthesized copolymers show excellent hemocompatibility under the conditions which mimic the real blood flow and possess great potentials for the applications in blood-contacting materials for biomedical devices.