Preparation of Protein loaded Core-Shell PEO/PLGA Ultrafine Fibers by Coaxial Electrospinning

摘要

Coaxial electrospinning technique has a number of advantages over conventional electrospinning. One of the advantages is to effectively protect easily denatured biological agents and wrap all substances in the core regardless of drug-polymer interactions. Also core-shell structure fibers electrospun from coaxial electrospinning can potentially provide a better therapeutic effect, reduced toxicity, and sustained drug release profile.