Breath analysis by electronic nose for Asthma detection

摘要

The aim of this paper is to determine Asthma by analyzing the Nitric oxide present in exhaled breath as a noninvasive method with the help of an electronic nose system based on Breath odor detection. Recognition of the presence of asthma in individuals is done by classifying the olfactory signal acquired through an electronic nose based on an array of sensors. Chemical compounds from the human body are important indicators which can be used for diagnosing human diseases. Electronic nose is an array of partially selective chemical sensor, where Nitric oxide is the Biomarker of Asthma. It is suggestive that measurements of exhaled NO can be clinically useful in noninvasive diagnosis as well as monitoring of inflammatory airway diseases. Exhaled NO levels were found higher in subjects with difficult asthma (mean 13.9 ppb, 95% CI 9.3 to 18.5) compared normal controls (7.4 ppb, 95% CI 6.9 to 7.8; p<0.002), however lower than levels in steroid naive mild asthmatics (36.9 ppb, 95% CI 34.6 to 39.3; p<0.001). Few doctors' measure's a patient's exhaled NO levels and helping them to decide for effective treatments as well as medication doses and may continue to measure for few more occasions for judging the response to treatment given.