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In Vitro Study of the Correlation between the Aortic Flow Field Affected by the Bileaflet Mechanical Valves and Coronary Circulation

机译:胆管瓣机械瓣影响的主动脉流场与冠脉循环的相关性的体外研究

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Three bi-leaflet prostheses, the St. Jude Medical (SJM) and the On-X valves with straight leaflets and the MIRA valves with curved leaflets were tested in the aortic position under pulsatile-flow condition to find the design and other influences on aortic flow field and coronary circulation. The flow field affected by the valve-installed orientations, leaflet shapes, and valve designs were analyzed using Dynamic PIV system. Direct measurement of the coronary flow using ultrasonic flow meter was used to monitor coronary flow. Detailed chronological comparison of the flow fields downstream of the aortic valve and inside the sinus of valsalva and coronary flow revealed the overall valve effect on the flow and possible influence on the coronary flow.Newer IVIIRA and On-X valves showed strong flow through the central orifice. The SJM and the newer On-X valve generate stronger circulatory flow inside the sinus of valsalva when valve orientation is set at 180° while the MIRA valve with curved leaflet generates stronger circulatory flow inside the sinus of valsalva when valve orientation is set at 90°. Coronary flow clearly shows the increase of flow rate when the circulatory flow inside the sinus of valsalva increase. This possibly indicate the positive correlation exist between the circulatory flow inside the sinus of valsalva and the coronary flow.
机译:在脉动流条件下,在主动脉位置测试了三片双瓣假体,分别是St. Jude Medical(SJM)和On-X直瓣瓣膜以及MIRA弯曲瓣膜瓣膜,以发现其设计以及对主动脉的其他影响流场和冠状动脉循环。使用Dynamic PIV系统分析了受阀门安装方向,小叶形状和阀门设计影响的流场。使用超声流量计直接测量冠状动脉血流量以监测冠状动脉血流量。对主动脉瓣下游以及瓣膜窦和冠状动脉血流内部流场进行详细的时间顺序比较,揭示了总体瓣膜对血流的影响以及可能对冠状动脉血流的影响。较新的IVIIRA和On-X瓣膜显示流经中央的强血流孔。当瓣膜方向设置为180°时,SJM和更新的On-X瓣膜在瓣膜窦内产生更强的循环血流,而当瓣膜方向设置为90°时,带有弯曲小叶的MIRA瓣膜在瓣膜窦内产生更强的循环血流。 。当瓣膜窦内的循环血流增加时,冠状动脉血流清楚地显示出流速的增加。这可能表明在valsalva窦内部的循环血流与冠状动脉血流之间存在正相关。

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