SCREENING OF SECONDARY METABOLITES FROM XYLEM OF EUCOMMIA ULMOIDES

摘要

Engineering, Tianjin University of Science and Technology, Tianjin 300457,China;Hai-Yan Hu@Tianjin Key Laboratory of Pulp and Paper, College of Materials Science and Chemical Engineering, Tianjin University of Science and Technology, Tianjin 300457,China;Yan-Fang Su@School of Pharmaceutical Science and Technology,Tianjin University, Tianjin 300072, China;Zhong Liu@Tianjin Key Laboratory of Pulp and Paper, College of Materials Science and Chemical Engineering, Tianjin University of Science and Technology, Tianjin 300457,China Eucommia ulmoides Oliv., the single species of the genus Eucommia and the family of Eucommiaceae, is a large medicinal hardwood native to China and widely cultured in Eastern Asia and has extensively been used as a tonic to strengthen the liver and kidneys, strong bones, against diabetics, lower blood pressure, treat lower back pain, ache knees, prevent miscarriage and fatigue. In order to screen the secondary metabolites of this medicinal tree, six yellow amorphous phenolic compounds, including gallic acid, ellagic acid, caffeic acid, kaempferol, wogonin, and astragalin, were isolated from nbuthanol soluble fraction of acetone extracts from E. ulmoides xylem in this work. The structures of the isolated secondary metabolites were mainly elucidated and established by spectroscopic analysis, such as ID and 2D NMR and MS (El, FAB and MALDI-TOF), as well as cellulose TLC and other physical and chemical evidences. To the best of our knowledge, this was the first time of screening secondary metabolites of E. ulmoides xylem.