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Analysing Structure in Complex Networks Using Quality Functions Evolved by Genetic Programming

机译:利用遗传规划演化的质量函数分析复杂网络中的结构

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When studying complex networks, we are often interested in identifying structures within the networks. Previous work has successfully used algorithmically identified network structures to predict functional groups; for example, where structures extracted from protein-protein interaction networks have been predictive of functional protein complexes. One way structures in complex networks have previously been described is as collections of nodes that maximise a local quality function. For a particular set of structures, we search the space of quality functions using Genetic Programming, to find a function that locally describes that set of structures. This technique allows us to investigate the common network properties of defined sets of structures. We also use this technique to classify and differentiate between different types of structure. We apply this method on several synthetic benchmarks, and on a protein-protein interaction network. Our results indicate this is a useful technique of investigating properties that sets of network structures have in common.
机译:在研究复杂的网络时,我们通常对识别网络中的结构感兴趣。先前的工作已经成功地使用算法确定的网络结构来预测功能组。例如,从蛋白质-蛋白质相互作用网络中提取的结构可预测功能性蛋白质复合物。先前已经描述了复杂网络中的结构的一种方式是最大化本地质量功能的节点集合。对于一组特定的结构,我们使用遗传编程搜索质量函数的空间,以找到局部描述该组结构的函数。这种技术使我们能够研究定义的结构集的公共网络属性。我们还使用此技术对不同类型的结构进行分类和区分。我们在几种合成基准和蛋白质-蛋白质相互作用网络上应用此方法。我们的结果表明,这是研究网络结构集共有的属性的有用技术。

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