In this paper, we report a neural probe which can selectively stimulate target neurons optically through Si wet etched mirror surface and record extracellular neural signals in iridium oxide tetrodes. Consequently, the proposed approach provides to improve directional problem and achieve at least 150/m gap distance between stimulation and recording sites by wet etched mirror surface in V-groove. Also, we developed light source, blue laser diode (OSRAM Blue Laser Diode_PL 450), integration through simple jig for one-touch butt-coupling. Furthermore, optical power and impedance of iridium oxide tetrodes were measured as 200μW on 5mW from LD and 206.5kΩ at 1kHz and we demonstrated insertion test of probe in 0.5% agarose-gel successfully. We have successfully transmitted a light of 450nm to optical fiber through the integrated LD using by butt-coupling method.
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机译：在本文中，我们报告了一种神经探针，该探针可以选择性地通过Si湿蚀刻镜面光学刺激目标神经元，并在四氧化二铱中记录细胞外神经信号。因此，所提出的方法提供了改进的方向性问题，并且通过在V形槽中湿蚀刻的镜面实现了刺激和记录部位之间的至少150 / m的间隙距离。此外，我们还开发了光源，蓝色激光二极管（OSRAM Blue Laser Diode_PL 450），通过简单的夹具集成在一起，实现了一触式对接。此外，在距LD 5mW处测得的氧化铱四极体的光功率和阻抗为200μW，在1kHz处测得为206.5kΩ，我们成功地证明了探针在0.5％琼脂糖凝胶中的插入测试。我们已经通过对接耦合方法成功地将450nm的光通过集成的LD传输到光纤。
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