Accelerated surface plasmon resonance biosensing by surface acoustic waves microstreaming

摘要

This paper describes our design incorporating surface plasmon resonance biosensing and surface acoustic wave active microfluidic mixing, integrated on a single LiNbO3 piezoelectric substrate. Validation experiments show that surface acoustic wave-induced microstreaming results in significant accelerated binding kinetics in a case of a standard avidin-biotin affinity assay.