bCloudBLAST: An efficient mapreduce program for bioinformatics applications

摘要

The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. We present an improved MapReduce-parallel implementation by splitting both of input query sequence files and sequence databases for search, called bCloudBLAST, showing very good scaling and speedup behavior on large sequence database. bCloudBLAST is written in Java, executable on UNIX/Linux, Windows and NacOS systems. (Free) MapReduce and Hadoop libraries can be found at http://hadoop.apache.org/. For download: http://www.darwintree.cn/tools.htm