Graphite Oxide Nanoparticles Larger than 20nm in Diameter are Biocompatible with Mouse Embryonic Stem Cells

摘要

Small GO particles with diameter <20 nm suppressed cell growth, luciferase gene expression, and increased cell death. Higher concentrations of GO in all sizes also had detrimental effects on mESC growth. GO particles larger than 20 nm in 0.005 mg/ml are biocompatible and can be safely used for mESCs.