Maximum likelihood parameter estimation in a stochastic resonate-and-fire neuronal model

摘要

Recent work has shown that resonate-and-fire model is both computationally efficient and suitable for large network simulations. In this paper, we examine the estimation problem of a resonate-and-fire model with random threshold. The model parameters are divided into two sets. The first set is associated with subthreshold behavior and can be optimized by a nonlinear least squares algorithm. The other set contains threshold and reset parameters and its estimation is formulated in terms of maximum likelihood formulation. We evaluate such a formulation with detailed Hodgkin-Huxley model data.