We report dual-functional hollow gold nanospheres (HAuNS, ~40-nm diameter) capable of mediating both photothermal ablation of cancer cells and drug release upon near-infrared (NTR) light irradiation. As high as 63% DOX by weight (-1.7 ng DOX/μg Au) could be loaded to polyethylene glycol-coated HAuNS (PEG-HAuNS) since DOX was coated to both the outer and the inner surfaces of HAuNS.
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机译:我们报告双功能空心金纳米球(HAuNS,〜40纳米直径)能够介导癌细胞的光热消融和近红外(NTR)光照射下的药物释放。由于DOX既被涂覆在HAuNS的内外表面上,也可以将高达63%重量的DOX(-1.7 ng DOX /μgAu)加载到聚乙二醇涂层的HAuNS(PEG-HAuNS)上。
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