Softgel Capsule Containing Polysaccharide Microspheres as Colon Targeting Drug Delivery System

机译：含多糖微球作为结肠靶向给药系统的软胶囊

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A softgel capsule dosage form comprising enteric soft shell encapsulated with API-loaded polysaccharide microspheres was designed and tested for colon specific drug delivery application. The results showed an API protection in acidic medium, slow release in small intestine condition, and accelerated release in colon condition.

机译：设计并测试了软胶囊胶囊剂型，其包括用载有API的多糖微球封装的肠溶软壳，并测试了其在结肠特异性药物递送中的应用。结果表明，API在酸性介质中具有保护作用，在小肠条件下缓慢释放，而在结肠条件下则加速释放。

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《Annual meeting exposition of the Controlled Release Society》|2011年|p.597-598|共2页
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Yunhua Hu. Qi Fang; Ning Yu; Shingai Majuru;
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中图分类系统科学;
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2. Hydroxyapatite nanowhiskers embedded in chondroitin sulfate microspheres as colon targeted drug delivery systems [J] . Cellet T. S. P., Pereira G. M., Muniz E. C., Journal of Materials Chemistry, B. materials for biology and medicine . 2015,第33期

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3. Effect of co-administration of probiotics with polysaccharide based colon targeted delivery systems to optimize site specific drug release [J] . Prudhviraj G., Vaidya Yogyata, Singh Sachin Kumar, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2015,第Pta1期

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Softgel Capsule Containing Polysaccharide Microspheres as Colon Targeting Drug Delivery System

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