Application of Hierarchical Cluster Analysis in the Classification of Pentacyclic Triterpenoids and Their Salt Derivatives

摘要

Eight kinds of salt derivatives of triterpene acids were prepared. The cluster analysis was applied for the study of ursolic acid, oleanolic acid and 8 salt derivatives, according to the measured value of water-solubility and antibacterial activity. The results of cluster analysis showed that the ten compounds can be clustered into three groups approximately. Most of the compounds have great similarities in biological activity.