The analysis of morbidity by a cancer of a thyroid gland of children on the moment of an exposure I131 owing to Chernobyl accident, registered in the Uniform Chernobyl register of Russia and Belarus

摘要

The main characteristics of cohort of the observation generated by indicated criteria: number 65575person, including in the Gomel area 25215, in Bryansk - 40360, number of the registered cases of disease 226,including 132 in the Gomel area and 94 in Bryansk area, number of person-years of observation 1021229,including in the Gomel area 391363 of observation, in Bryansk - 629866, average exposure dose of a thyroidgland by radioisotopes of ~(131)I in cohort 0,71 Gy, in the Gomel area 1,5 Gy, in Bryansk area - 0,2 Gy. Estimated arole of radiation and various not radiation risk factors, such as a sex, age on the moment of an exposure. Theanalysis of not radiation risk factors is spent separately for the Gomel area, Bryansk area and joined cohort.Among the persons irradiated in children's age in the Gomel area, the risk of disease by a cancer of a thyroidgland among the boys and girls was identical (RR=1,02, 95 % CI 0,72-1,44), in too time in Bryansk area the riskof disease of the girls in 3,4 times was higher (95 % CI 2,0-5,6), than among the boys. In joined cohort the girl in1,5 times more often were sick of a cancer of a thyroid gland (95 % CI 1,16-2,0) in comparison with the boys.The analysis dose of dependence of a case rate by a cancer of a thyroid gland among the persons irradiated inchildren's age, has shown presence of a linear relation dose - effect, and in joined cohort this dependence moststatistically is significant (у=0,002х+0,86, R~2=0,99). The value of exuberant relative risk on a dose 1 Gy hasmade 4,54 (95 % CI 2,43-9,78).