Silica-on-silicon (SOS)-PDMS platform integrated Lab-on-a-chip (LOC) forQuantum Dot applications

摘要

Integration of microfluidics with the integrated optical waveguides enables the realization of devices capable of performing the biodetection and analysis on small scale using fluorescence biolabels such as Quantum Dot (QD). Polydimethylsiloxane (PDMS) has been an excellent choice to build the optical bio-microfluidic systems because of its biocompatibility, optical properties and low cost fabrication process. In this work, we report a method to integrate the microfluidics channels and waveguides fabricated on Silica-on-silicon (SOS) and PDMS platform for the realization of a Lab-on-a-chip (LOC). Performance of the device tested by measuring fluorescence from the laser excited Quantum Dot (QD655) solution reveals that the developed device is suitable for performing the QD based biodetection and analysis efficiently.