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Numerical investigation of the hemodynamics in anatomically realistic lateral cerebral aneurysms

机译:解剖学上真实的侧脑动脉瘤血流动力学的数值研究

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Hemodynamically induced stress plays an important role in the progression and rupture of cerebral aneurysms. The current work describes computational fluid dynamics (CFD) simulations in anatomically realistic models of cerebral aneurysms. Twenty lateral aneurysms models were investigated. The models were obtained from three-dimensional rotational angiographic imaging data and CFD were studied under the same physiologically representative waveform of inflow. The flow was assumed to be laminar, non-Newtonian, and incompressible. The CFD models were solved with the finite elements package ADINA. Predictions of velocity field and wall shear stress (WSS) on the aneurysms were compared for the different cases. Linear correlations between the WSS on the aneurysm fundus at peak systole for lateral aneurysms with an area index were found.
机译:血流动力学诱发的应激在脑动脉瘤的进展和破裂中起着重要作用。当前的工作描述了脑动脉瘤的解剖学逼真的模型中的计算流体动力学(CFD)模拟。研究了二十种外侧动脉瘤模型。从三维旋转血管造影成像数据获得模型,并在相同的生理代表性流入波形下研究CFD。假定流动为层流,非牛顿流和不可压缩流。使用有限元软件包ADINA解决了CFD模型。比较了不同情况下对动脉瘤的速度场和壁切应力(WSS)的预测。发现具有面积指数的外侧动脉瘤的收缩期峰值时,动脉瘤眼底WSS之间的线性相关性。

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