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Hardware computing for brain network analysis

机译:用于大脑网络分析的硬件计算

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As the scale of computer clusters and supercomputers is getting larger, the problem of power consumption and heat dissipation has become the biggest obstacle for the ever growing need for computation. Designing platforms for specific applications using the reconfigurable logic such as Field Programmable Gate Arrays (FPGAs) or highly parallel processors such as Graphic Processing Units (GPUs) will dramatically increase power efficiency. This is the concept of domain specific computing. Combining the advantages of different platforms to build a heterogeneous computing platform is the trend of domain specific computing. On the other hand, the research on brain networks plays a vital role in understanding the connectivity patterns of the human brain and disease-related alterations. Recent studies have suggested a noninvasive way of modeling and analyzing the human cortical networks with MRI by graph theory based approaches. However, both the construction and analysis of brain networks require tremendous computation. Currently, only hundreds of nodes can be analyzed due to lack of computing power. By increasing the number of nodes, the resolution of cortical networks will be greatly enhanced, thus hopefully helps the early diagnosis of brain diseases such as Alzheimer's disease. A well-designed computing platform is the key to this problem. In this work, we inject the power of heterogeneous hardware computing into the brain network research, to help the research on the connectivity patterns of both normal and diseased brains. Besides, one important outcome is an accelerated BLAS and Graph algorithms package, which will provide insights into domain specific computing to boarder audience in both biomedical and computer science domains.
机译:随着计算机集群和超级计算机的规模越来越大,功耗和散热问题已成为不断增长的计算需求的最大障碍。使用可重配置逻辑(例如现场可编程门阵列(FPGA)或高度并行的处理器,例如图形处理单元(GPU))为特定应用设计平台将大大提高电源效率。这是领域特定计算的概念。结合不同平台的优势来构建异构计算平台是领域特定计算的趋势。另一方面,对大脑网络的研究在理解人脑和疾病相关变化的连通性模式方面起着至关重要的作用。最近的研究提出了一种无创的方法,通过基于图论的方法,利用MRI对人体皮质网络进行建模和分析。但是,大脑网络的构建和分析都需要大量的计算。目前,由于缺乏计算能力,只能分析数百个节点。通过增加结点数量,皮质网络的分辨率将大大提高,从而有望帮助早期诊断脑部疾病,例如阿尔茨海默氏病。设计良好的计算平台是解决此问题的关键。在这项工作中,我们将异构硬件计算的功能注入到大脑网络研究中,以帮助研究正常和患病大脑的连接模式。此外,一项重要的成果是加速了BLAS和Graph算法程序包,它将为生物医学和计算机科学领域的专业人士提供对领域特定计算的见解。

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