Carbon Nanotube Assisted Laser Thermotherapy of Skin Cancers – Pilot Proof-of-Principle Study in a Murine Model

摘要

Ten groups of mice were exposed to 785 nm laser after intratumoral injection of single-wall carbon nanotubes (SWNTs). The temperature within the tumors increased in a light- and drug-dose dependent manner; optimized light and drug dose combinations resulted in eradication of skin tumors. SWNTs persisted within the tumor tissue for months.