ZINC ALUMINUM LAYER DOUBLE HYDROXIDE IBUPROFEN PLLA NANOCOMPOSITES: SYNTHESIS, STRUCTURE AND CHARACTERIZATION

摘要

The purpose of this research was to study the intercalation of the anions of Ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDs), α-mefhyl-4-(2-methyipropyl)-benzene acetic acid into a layer double hydroxide (Zn-Al LDH) to form a new organic-inorganic hybrid intercalated material and the formation of nanocomposite with Poly (1-Lactic acid) (PLLA). The synthesis was achieved through two steps. The first step is the modification of layer double hydroxide with Ibuprofen anions. The second is the dispersion of the LDH into PLLA. The resulting organo-inorganic hybrid material was characterized by X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), and Tensile Test. X-ray diffraction evinces the presence of dispersion of LDH and intercalation.