Microemulsions for topical delivery of 5-aminolevulinic acid and its hexil ester inPhotodynamic Therapy

机译：微乳剂在光动力疗法中局部递送5-氨基乙酰丙酸及其己酸酯

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5-aminolevulinic acid (5-ALA) and its hexil ester (H-ALA) were incorporated in microemulsions (ME) and their skin retention and permeation were studied. Results showed that microemulsion retarded release of drugs compared with a water solution. Oil-in-water ME increased significantly skin retention and permeation of 5-ALA in contrast to H-ALA results.

机译：将5-氨基乙酰丙酸（5-ALA）及其己酸酯（H-ALA）掺入微乳液（ME）中，并对它们的皮肤保留和渗透性进行了研究。结果表明，与水溶液相比，微乳液可延缓药物的释放。与H-ALA结果相比，水包油ME显着提高了5-ALA的皮肤保留和渗透性。

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《Controlled Release Society Annual Meeting and Exposition》|2007年|P.1562-1563|共2页
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Luciana Mattoso Pires de Campos; Renata Fonseca Vianna Lopez;
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中图分类生物工程学（生物技术）;
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1. Development of microemulsions to topically deliver 5-aminolevulinic acid in photodynamic therapy. [J] . Araujo LM, Thomazine JA, Lopez RF European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2010,第1期

机译：在光动力疗法中开发微乳液以局部递送5-氨基乙酰丙酸。
2. Microneedle Pre-treatment of Human Skin Improves 5-Aminolevulininc Acid (ALA)- and 5-Aminolevulinic Acid Methyl Ester (MAL)-Induced PpIX Production for Topical Photodynamic Therapy Without Increase in Pain or Erythema [J] . Patrycja Mikolajewska, Ryan F. Donnelly, Martin J. Garland, Pharmaceutical Research . 2010,第10期

机译：人类皮肤的微针预处理可以改善5-氨基乙酰丙酸（ALA）和5-氨基乙酰丙酸甲酯（MAL）诱导的PpIX的生产，以进行局部光动力疗法，而不会增加疼痛或红斑
3. Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema. [J] . Mikolajewska P, Donnelly RF, Garland MJ, Pharmaceutical research . 2010,第10期

机译：人体皮肤的微针预处理可改善5-氨基乙酰丙酸（ALA）和5-氨基乙酰丙酸甲酯（MAL）诱导的PpIX的产生，以进行局部光动力疗法，而不会增加疼痛或红斑。
4. Microemulsions for topical delivery of 5-aminolevulinic acid and its hexil ester inPhotodynamic Therapy [C] . Luciana Mattoso Pires de Campos, Renata Fonseca Vianna Lopez Controlled Release Society Annual Meeting and Exposition . 2007

机译：用于局部递送5-氨基乙酰丙酸及其己烯酯的微型乳液，其含有电力学疗法
5. Formulation and evaluation of microemulsions as topical drug delivery vehicle for an antimicrobial drug. [D] . Patel, Mrunali Rashmin. 2011

机译：微乳剂的配制和评估，作为抗微生物药物的局部给药载体。
6. Stratum corneum lipids liposomes for the topical delivery of 5-aminolevulinic acid in photodynamic therapy of skin cancer: preparation and in vitro permeation study [O] . Maria Bernadete R Pierre, Antônio C Tedesco, Juliana M Marchetti, 2001

机译：角质层脂质脂质体在皮肤光动力疗法中局部递送5-氨基乙酰丙酸的用途：制备和体外渗透研究
7. Stratum corneum lipids liposomes for the topical delivery of 5-aminolevulinic acid in photodynamic therapy of skin cancer: preparation and in vitro permeation study [O] . Pierre, Bernadete R M, Tedesco, Antônio C, Marchetti, Juliana M, 2015

机译：角质层脂质脂质体在皮肤光动力疗法中局部递送5-氨基乙酰丙酸的用途：制备和体外渗透研究
8. Topical Hazard Evaluation Program of Candidate Insect Repellent AI3-70763 3(N-n-Butly-N-Acetyl) Aminopropionic Acid-Ethyl Ester December 1976 - April 1977. [R] . Weeks, M. H., DeSean, B. J. 1977

机译：候选驱虫剂aI3-70763 3（N-正丁基-N-乙酰基）氨基丙酸 - 乙基酯的局部危害评估程序1976年12月 - 1977年4月。

Microemulsions for topical delivery of 5-aminolevulinic acid and its hexil ester inPhotodynamic Therapy

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