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Cytotoxicity of perfluorocarbon-based emulsion oxygen carriers

机译:全氟化碳基乳液氧载体的细胞毒性

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Emulsion preparations of perfluorooctyl bromide (PFOB) and egg yolk phospholipid (EYP) and their cytotoxicity for their use as oxygen carriers were studied. Size distribution of the particles broadened following 14-day storage. Primary human fibroblasts exposure to PFOB/EYP emulsions permanently inhibited cell proliferation and decreased mitochondrial activity.
机译:研究了全氟辛基溴化物(PFOB)和蛋黄磷脂(EYP)的乳液制剂及其用作氧载体的细胞毒性。储存14天后,颗粒的尺寸分布变宽。初级人类成纤维细胞暴露于PFOB / EYP乳剂可永久抑制细胞增殖并降低线粒体活性。

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