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The Influence of Solvent System on the Performance of Polyvinyl Acetate Phthalate (PVAP) Delayed ReleaseCoating Systems

机译:溶剂体系对邻苯二甲酸乙烯酯(PVAP)延迟释放系统性能的影响

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摘要

Polyvinyl acetate phthalate (PVAP) or a fully-formulated delayed release coating system based on PVAP were dispersed in different solvents. Dispersion properties and coated tablet delayed release performance were evaluated. The neat polymer and formulated system yielded physically stable dispersions while the formulated system provided acceptable enteric protection and tablet disintegration.
机译:邻苯乙烯酯(PVAP)或基于PVAP的完全配制的延迟释放涂料系统分散在不同的溶剂中。评估分散性质和涂层片剂延迟释放性能。整齐的聚合物和配制的体系在物理上稳定的分散体,而配制的体系提供了可接受的肠溶保护和片剂崩解。

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