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Micelles from Cholesteryl-Conjugated siRNA and Polyethylene Glycol-Phosphatidylethanolamine (PEG-PE) for Enhanced Intracellular Delivery of siRNA

机译：胆固醇缀合的siRNA和聚乙二醇-磷脂酰乙醇胺（PEG-PE）的胶束可增强siRNA的细胞内递送

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摘要

PEG-PE and cholsteryl-modified siRNA (siRNA-Chol) form stable mixed micelles with high content of siRNA. These micelles are easily taken up by the cells and can be used as an effective mean to deliver siRNA inside cells.

机译：PEG-PE和胆固醇修饰的siRNA（siRNA-Chol）形成稳定的混合胶束，且siRNA含量高。这些胶束很容易被细胞吸收，可以用作在细胞内传递siRNA的有效手段。

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《Controlled Release Society Annual Meeting and Exposition》|2007年|P.454-455|共2页
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作者
T.Levchenko; G. DSouza; R.K.Pandey; M.A. Maier; M. Manoharan; V.P. Torchilin;
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中图分类生物工程学（生物技术）;
关键词
polymeric micelles; mixed micelles; sirna; peg-pe;

机译：聚合物胶束;混合胶束; sirna; peg-pe;

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专利

1. Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin e micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer [J] . AbouzeidA.H., PatelN.R., TorchilinV.P. International Journal of Pharmaceutics . 2014,第1a2期

机译：聚乙二醇-磷脂酰乙醇胺（PEG-PE）/维生素胶束共同递送紫杉醇和姜黄素，以克服卵巢癌的多药耐药性
2. Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide [J] . Lee SH, Kim SH, Park TG Biochemical and Biophysical Research Communications . 2007,第2期

机译：使用由VEGF siRNA-PEG共轭物和阳离子融合肽制备的聚电解质复合胶束的细胞内siRNA递送系统
3. Enhanced Intracellular Delivery of siRNA by Controlling ATP‐Responsivity of Phenylboronic Acid‐Functionalized Polyion Complex Micelles [J] . Naito Mitsuru, Yoshinaga Naoto, Ishii Takehiko, Macromolecular bioscience . 2018,第1期

机译：通过控制苯基硼酸官能化聚硫胶的ATP响应性增强SiRNA的细胞内递送
4. Micelles from Cholesteryl-Conjugated siRNA and Polyethylene Glycol-Phosphatidylethanolamine (PEG-PE) for Enhanced Intracellular Delivery of siRNA [C] . T.Levchenko, G. DSouza, R.K.Pandey, Controlled Release Society Annual Meeting and Exposition . 2007

机译：来自胆固醇缀合的siRNA和聚乙二醇 - 磷脂酰乙醇胺（PEG-PE）的胶束，用于增强siRNA的细胞内递送
5. A-B-C Triblock Copolymer Micelles for Intracellular Delivery of Cancer-Targeted siRNA [D] . Gary, Dana Jeanine. 2010

机译：A-B-C三嵌段共聚物胶束，用于细胞内递送靶向癌症的siRNA
6. Intracellular Delivery of siRNAs Targeting AKT and ERBB2 Genes Enhances Chemosensitization of Breast Cancer Cells in a Culture and Animal Model [O] . Tahereh Fatemian, Hamid Reza Moghimi, Ezharul Hoque Chowdhury 2019

机译：靶向AKT和ERBB2基因的siRNA的细胞内传递增强了乳腺癌细胞在培养和动物模型中的化学敏感性
7. Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer [O] . Abraham H. Abouzeid, Niravkumar R. Patel, Vladimir P. Torchilin 2014

机译：聚乙二醇 - 磷脂酰乙醇胺（PEG-PE）/维生素E胶束用于紫杉醇和姜黄素的共递送，以克服卵巢癌中的多种耐药性

Micelles from Cholesteryl-Conjugated siRNA and Polyethylene Glycol-Phosphatidylethanolamine (PEG-PE) for Enhanced Intracellular Delivery of siRNA

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